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The active ingredient present in Cymbalta is Duloxetine hydrochloride and inactive ingredients in the drug include Hypromellose, gelatin, Hydroxypropyl, sodium lauryl sulfate, methylcellulose acetate succinate, sugar spheres, sucrose, sugar, titanium dioxide and triethyl citrate. Twenty and sixty mg of Cymbalta capsules contains yellow iron oxide.
How Does Cymbalta Work?
There are numerous chemical compound called neurotransmitters in the brain that serve as chemical messengers between the nerve cells. Serotonin and noradrenaline are two neurotransmitters which when released from nerve cells in the brain help in improving mood. When these neurotransmitters get reabsorbed in the nerve cells these neurotransmitters prove no more effective on mood. In depression it is believed that there is a lesser amount of serotonin and noradrenaline neurotransmitters released from nerve cells found in the brain. Duloxetine is believed to work by preventing these neurotransmitters from being reabsorbed into the nerve cells in the brain, thereby prolonging its mood lightening effect. Thus, Duloxetine helps in relieving depression.