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Diovan HCT comprises of both active and inactive ingredients.
Active Ingredients – Valsartan and hydrochlorothiazide are the active ingredients of the drug.
Inactive Ingredients – Inactive ingredients in Diovan HCT include colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, iron oxides, magnesium stearate, microcrystalline cellulose, polyethylene glycol, talc and titanium dioxide.
How Diovan HCT Works?
Diovan HCT, a combination of two medicines Diovan and hydrochlorothiazide, helps in reducing high blood pressure in two ways. Diovan is an angiotensin II receptor blocker that blocks angiotensin II receptors. By blocking the receptors, effectiveness of the chemical angiotensin II is decreased. This chemical usually narrows the blood vessels that lead to high blood pressure. Therefore, by blocking the effect of the chemical angiotensin II, Diovan HCT causes blood vessels to relax thereby reducing the blood pressure.
The presence of the other drug Hydrochlorothiazide, commonly referred as a water pill, also helps in reducing the pressure. It works by increasing the amount of salt and water removed by the kidneys from the blood. The extra amount of salt and water extracted from the blood is eliminated from the body through the urine. Therefore, by increasing the water and salt removed from the blood, hydrochlorothiazide causes a decrease in blood pressure. The combined effect of both the drugs causes a significant drop in the blood pressure compared to most single blood pressure medication.