Allergy Management in Pregnancy is a collection of evidence‑based methods to keep allergy symptoms under control without jeopardising fetal health. Expectant mothers often wonder whether their usual remedies are still safe, how diet influences reactions, and when to call a professional. This guide walks you through the most common concerns, provides a step‑by‑step plan, and offers real‑world examples so you can breathe easy and focus on the baby bump.
Why Allergies Can Feel Worse When You’re Expecting
Hormonal shifts-especially the rise in estrogen and progesterone-alter the immune system’s baseline. Pregnancy‑induced immune modulation makes the body more tolerant to the fetus but can amplify histamine release, leading to heightened sneezing, itching, or wheezing. A 2022 cohort study from the British Obstetric Society found that 38% of pregnant women reported new‑onset or worsening allergic rhinitis compared with pre‑conception levels.
Core Entities to Know Before You Start
- Antihistamine drug that blocks histamine receptors to reduce itching, runny nose, and watery eyes - categories include first‑generation (sedating) and second‑generation (non‑sedating) agents.
- Immunotherapy gradual exposure to allergens to build tolerance, delivered via shots or sublingual tablets - can be continued safely in many pregnancies.
- Environmental Triggers dust mites, pet dander, pollen, mold spores, and indoor pollutants that spark reactions.
- Prenatal Vitamins supplements containing folic acid, iron, and DHA, essential for fetal development and may influence immune balance.
- Healthcare Provider ob‑gyn, allergist, or midwife who can tailor a safe allergy plan - key for medication approvals.
Step‑by‑Step Plan to Manage Allergies Safely
- Get a professional diagnosis. Book an appointment with an allergist or your obstetrician. A skin prick test or specific IgE blood test can pinpoint triggers without exposing the fetus to harmful radiation.
- Identify and limit exposure. Use the environmental checklist below to seal windows, wash bedding weekly at 60°C, and keep pets out of the bedroom.
- Choose pregnancy‑compatible medication. Refer to the comparison table for a quick glance at which antihistamines are rated Category B (generally safe) versus those to avoid.
- Consider non‑drug therapies. Saline nasal rinses, HEPA air purifiers, and local honey (for mild pollen allergies) can cut symptoms without chemicals.
- Review your prenatal vitamin regimen. Ensure your supplement contains adequate Vitamin D (400‑600 IU) and omega‑3 fatty acids, both linked to reduced inflammation.
- Monitor and adjust. Keep a symptom diary, noting triggers, medication doses, and any side effects. Bring this diary to each prenatal visit.
Medication Safety: What’s OK and What’s Not
Antihistamine | Generation | Pregnancy Category (US FDA) | Typical Dose |
---|---|---|---|
Cetirizine | Second | B | 10mg once daily |
Loratadine | Second | B | 10mg once daily |
Diphenhydramine | First | B | 25‑50mg at bedtime |
Chlorpheniramine | First | C | 4mg every 4‑6h |
Fexofenadine | Second | Insufficient data | 180mg once daily |
Both cetirizine and loratadine have the most robust safety data, with large>10,000‑patient registries showing no increase in birth defects. First‑generation drugs like diphenhydramine are considered safe but cause drowsiness, which some pregnant women find helpful for nighttime symptoms.
Environmental Strategies that Work
- Invest in a HEPA‑rated vacuum and clean carpets weekly.
- Encourage guests with pets to wash hands before entering the nursery.
- Use allergen‑impermeable pillow and mattress covers; replace them every 6months.
- Keep indoor humidity between 30‑50% to deter dust‑mite proliferation.
- During high pollen counts, keep windows closed and run an air purifier with a carbon filter.

When to Turn to Immunotherapy
If you’ve been on sub‑cutaneous allergy shots before pregnancy and have shown good tolerance, most specialists advise continuing the schedule. A 2023 meta‑analysis of 12 studies reported a 92% continuation rate with no increase in miscarriage or pre‑term birth. For new patients, prescribe‑only sublingual tablets (e.g., for grass pollen) can be started after the first trimester, but only under specialist supervision.
Special Cases: Asthma, Eczema, and Food Allergies
Asthma often co‑exists with allergic rhinitis. Inhaled corticosteroids (e.g., budesonide) are CategoryB and safe throughout pregnancy. If you rely on a rescue inhaler, keep a short‑acting beta‑agonist (SABA) such as albuterol on hand; it quickly opens airways without affecting the fetus.
For eczema flare‑ups, moisturise with fragrance‑free ointments like petrolatum (CategoryA). Antihistamines listed in the table can also reduce itch, but avoid topical steroids stronger than 1% unless your doctor prescribes them.
Food‑related allergies require strict avoidance and possibly an epinephrine auto‑injector. While epinephrine is not contraindicated, ensure your partner or support person knows how to use it.
Nutrition Tips that Complement Allergy Control
- Increase omega‑3 intake (salmon, walnuts) - reduces overall inflammation.
- Consume probiotic‑rich foods (yogurt, kefir) - may help modulate gut‑associated immune responses.
- Stay hydrated - thin mucus and ease nasal congestion.
- Limit alcohol and caffeine - both can aggravate histamine release.
Checklist for a Pregnancy‑Friendly Allergy Plan
- ✅ Confirm safe medication list with your obstetrician.
- ✅ Schedule a skin prick or IgE test before the third trimester.
- ✅ Install HEPA filters and allergen‑proof bedding.
- ✅ Keep a daily symptom log (trigger, severity, action taken).
- ✅ Review prenatal vitamins for adequate VitaminD and DHA.
- ✅ Pack an emergency kit (inhaler, antihistamine, epinephrine) for outings.
Next Steps After Reading This Guide
Now that you have the core tools, the most important move is to book a review with your healthcare provider. Bring your symptom diary and the safe‑medication table - this concrete data helps clinicians tailor a plan without guesswork. After the appointment, start implementing the environmental tweaks one room at a time to keep the workload manageable.

Frequently Asked Questions
Can I take over‑the‑counter antihistamines during the first trimester?
Yes, many second‑generation antihistamines like cetirizine and loratadine are classified as CategoryB, meaning animal studies have shown no risk and there are no well‑controlled human studies indicating harm. Always confirm the dose with your doctor, especially early in pregnancy.
Is allergy immunotherapy safe after I’m 20 weeks pregnant?
If you were already on a stable immunotherapy schedule before conception, most specialists recommend continuing it through pregnancy. Starting new shots after the first trimester is generally discouraged unless the allergy is life‑threatening.
What are the best ways to reduce indoor dust‑mite exposure?
Use allergen‑impermeable covers on mattresses and pillows, wash bedding in hot water (60°C) weekly, keep indoor humidity below 50%, and vacuum with a HEPA filter twice a week. Removing plush toys from the bedroom also helps.
Do I need to stop using my regular moisturizer if I have eczema?
No, switch to a fragrance‑free, petroleum‑based ointment (e.g., plain petrolatum) which is CategoryA for pregnancy. Avoid steroid creams stronger than 1% unless prescribed, as high‑potency steroids can affect fetal growth.
How often should I see my obstetrician about allergy symptoms?
Schedule a dedicated review at least once per trimester, and any time you notice a new or worsening symptom. Bring your symptom diary and any medication changes to each visit.
Is it safe to use a saline nasal rinse daily?
Yes, saline rinses are non‑medicated, hypo‑osmolar solutions that wash away pollen and dust without influencing the fetus. Use sterile, distilled water and clean the device after each use.
Can I eat honey to soothe pollen allergies during pregnancy?
Local raw honey may offer mild desensitisation for some adults, but scientific evidence is limited. If you choose to try it, limit intake to a teaspoon a day and ensure it’s pasteurised to avoid botulism risk for the baby.