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It contains the active ingredient tiotropium bromide and the inactive ingredient lactose monohydrate.
Mechanism (How Spiriva Works)
Acetylcholine is a natural chemical that acts on muscarinic receptors causing muscle surrounding the airways to contract. In chronic obstructive lung diseases the airways are narrowed which causes difficulty in breathing for the patients. Tiotropium is the main ingredient in Spiriva and is used for the treatment of COPD. Tiotropium belongs to an antimuscarinic or anticholinergic bronchodilator class of medication that works by opening the airways in the lungs. Tiotropium works by blocking the muscarinic receptors found on the airways muscle and thus, stops the action of acetylcholine on them. This allows the airways muscle to relax and open, making it easier for the patients to breathe.
