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Additional Considerations
When it comes to treating erectile dysfunction (ED), the market is flooded with options, and figuring out which one actually fits your lifestyle can feel overwhelming. This guide breaks down Tadarise compare by lining it up against the most common alternatives, so you can see the real differences in dosage, speed, duration, cost and safety.
Key Takeaways
- Tadarise is a 20mg tablet of tadalafil that starts working in 30‑60minutes and lasts up to 36hours.
- Generic tadalafil, Cialis and other branded PDE5 inhibitors have similar efficacy but differ in price and dosage flexibility.
- Natural supplements such as L‑arginine and yohimbine may help mild cases but lack the reliability of prescription pills.
- Side‑effects are generally mild; the biggest risks involve cardiovascular conditions and drug interactions.
- Choosing the right pill depends on how quickly you need it, how long you want the effect to last, and whether you prefer a prescription or over‑the‑counter option.
What is Tadarise?
Tadarise is a brand‑name tablet containing 20mg of tadalafil, a phosphodiesterase‑5 (PDE5) inhibitor designed to treat erectile dysfunction. It was launched in the UK in 2021 and quickly became popular for its "weekend‑pill" profile - rapid onset and a long window of effectiveness.
Key attributes of Tadarise:
- Typical dose: 20mg (single tablet)
- Onset: 30‑60minutes
- Duration: up to 36hours
- Price (2025 UK average): £19.99 per tablet
- Prescription: Required in the UK
How Tadarise Works
Tadalafil blocks the PDE5 enzyme, allowing cyclic guanosine monophosphate (cGMP) to accumulate in the penile tissue. More cGMP means better blood flow during sexual stimulation, resulting in a firmer erection. The long half‑life of tadalafil (≈17.5hours) is what gives Tadarise its extended window.

Major Alternatives to Tadarise
Below are the most frequently mentioned competitors, each defined with its own set of attributes.
Viagra is the trade name for sildenafil citrate, the first oral PDE5 inhibitor approved for ED.
- Typical dose: 50mg (range 25‑100mg)
- Onset: 30‑90minutes
- Duration: 4‑6hours
- Price (2025 UK average): £12.99 per tablet
- Prescription: Required
Cialis is a branded version of tadalafil, offered in 2.5mg, 5mg, 10mg and 20mg strengths for daily or as‑needed use.
- Typical dose: 10mg or 20mg (as‑needed); 2.5‑5mg for daily therapy
- Onset: 30‑60minutes
- Duration: up to 36hours
- Price (2025 UK average): £24.99 per 10mg tablet
- Prescription: Required
Levitra contains vardenafil, another PDE5 inhibitor with a profile similar to sildenafil.
- Typical dose: 10mg (range 5‑20mg)
- Onset: 25‑60minutes
- Duration: 4‑5hours
- Price (2025 UK average): £13.49 per tablet
- Prescription: Required
Stendra is the brand name for avanafil, a newer PDE5 inhibitor known for a very fast onset.
- Typical dose: 100mg (range 50‑200mg)
- Onset: 15‑30minutes
- Duration: 6‑12hours
- Price (2025 UK average): £28.99 per tablet
- Prescription: Required
L‑arginine is an amino‑acid supplement that may improve nitric‑oxide production, supporting natural erectile function.
- Typical dose: 2‑5g daily
- Onset: varies, often weeks of consistent use
- Duration: continuous while supplementing
- Price (2025 UK average): £8.99 per 500mg capsule bottle
- Prescription: Not required (over‑the‑counter)
Yohimbine is an herbal extract from the bark of Pausinystalia yohimbe, marketed for its potential ED benefits.
- Typical dose: 5‑10mg before sexual activity
- Onset: 30‑45minutes
- Duration: 4‑6hours
- Price (2025 UK average): £6.99 per 30‑tablet pack
- Prescription: Not required (but caution advised)
Side‑Effect Profile Across Options
All PDE5 inhibitors share a core set of possible side‑effects, though frequencies differ.
- Headache - most common with sildenafil and avanafil.
- Flushing - reported more with tadalafil.
- Indigestion - typical for sildenafil and vardenafil.
- Back‑pain - a hallmark of higher‑dose tadalafil (including Tadarise).
- Vision changes - rare, mostly linked to sildenafil.
Natural supplements usually cause milder gastrointestinal upset but can interact with blood pressure medications.
Direct Comparison Table
Brand | Active Ingredient | Typical Dose | Onset | Duration | Price per Tablet | Prescription? |
---|---|---|---|---|---|---|
Tadarise | Tadalafil | 20mg | 30‑60min | Up to 36h | £19.99 | Yes |
Viagra | Sildenafil | 50mg | 30‑90min | 4‑6h | £12.99 | Yes |
Cialis | Tadalafil | 10mg / 20mg | 30‑60min | Up to 36h | £24.99 | Yes |
Levitra | Vardenafil | 10mg | 25‑60min | 4‑5h | £13.49 | Yes |
Stendra | Avanafil | 100mg | 15‑30min | 6‑12h | £28.99 | Yes |
L‑arginine | Amino‑acid | 2‑5g daily | Weeks | Continuous | £8.99 | No |
Yohimbine | Herbal extract | 5‑10mg | 30‑45min | 4‑6h | £6.99 | No |

Decision Criteria: Which Pill Suits You?
Use the following checklist to narrow down the best option:
- Need for spontaneity? If you want a “take‑it‑when‑you‑need‑it” pill with a long window, tadalafil‑based products (Tadarise, Cialis) win.
- Fastest onset? Avanafil (Stendra) hits the fastest, useful for last‑minute plans.
- Budget constraints? Generic sildenafil (often sold under different names) is typically cheapest, while brand‑name avanafil sits at the top.
- Daily vs as‑needed? Low‑dose tadalafil (2.5‑5mg) offers daily dosing for those who prefer continual readiness; Tadarise is strictly as‑needed.
- Medical history? Anyone on nitrates, severe heart disease, or using alpha‑blockers should avoid PDE5 inhibitors and discuss alternatives with a GP.
Best‑Fit Scenarios
Weekend getaway - Tadarise or Cialis 20mg gives you a full 36‑hour window, perfect for spontaneous intimacy.
Quick date night - Stendra’s 15‑minute onset lets you act fast without waiting.
Cost‑conscious - Generic sildenafil (often under the name “Viagra‑like”) provides solid efficacy at a lower price per tablet.
Natural preference - L‑arginine can be added daily for mild support; however, don’t rely on it as a sole therapy if ED is moderate‑to‑severe.
Practical Tips & Common Pitfalls
- Always take the pill on an empty stomach for faster absorption (except avanafil, which is less affected by food).
- Avoid alcohol excess; it can dampen the drug’s effectiveness and increase side‑effects.
- Do not double‑dose if the first tablet hasn’t worked - give it at least one hour before considering another.
- Keep a record of how you feel-onset time, erection quality, and any side‑effects-to discuss with your doctor.
- Never share prescription pills; the dosage is individualized based on health status.
Frequently Asked Questions
Is Tadarise the same as generic tadalafil?
Tadarise contains the exact same active ingredient-tadalafil-as generic versions, but it’s marketed as a 20mg, fast‑acting tablet and often priced slightly higher than the unbranded product.
Can I take Tadarise with alcohol?
Moderate alcohol (one‑two drinks) usually won’t cancel the effect, but heavy drinking can reduce blood flow and increase the chance of headaches or dizziness.
How often is it safe to use Tadarise?
The recommended maximum is one dose per 24hours and no more than two doses per week unless a doctor advises otherwise.
What if I have high blood pressure?
Most PDE5 inhibitors are safe for controlled hypertension, but you must avoid them if you’re on nitrate medication. A quick check with your GP is essential.
Are natural supplements like L‑arginine effective?
L‑arginine can boost nitric‑oxide levels, offering modest help for mild ED, but it rarely matches the reliability of prescription PDE5 inhibitors for moderate‑to‑severe cases.